Polycythemia Vera & Myelofibrosis

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Polycythemia Vera & Myelofibrosis

The Janus kinase 2 (JAK2) gene directs cells to make the JAK2 protein, which stimulates cell growth and division. The Janus kinase 2 (JAK2) gene directs cells to make the JAK2 protein, which stimulates cell growth and division. The JAK2 protein is particularly important for controlling blood cell production from hematopoietic (blood-forming) stem cells.These

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How Treatment Improves Polycythemia Vera Life Expectancy

Polycythemia vera is a rare red blood cell cancer affecting blood flow in the body. Learn what researchers know about polycythemia vera life expectancy. Polycythemia vera is a medical condition that causes the body to make too many red blood cells. It is classified as a type of cancer. The excess red blood cells can cause dangerous complications such as blood clots, but the red blood cells do not

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Diagnosis of Polycythemia Vera

Polycythemia vera is diagnosed based on blood tests that measure hemoglobin, hematocrit, and a genetic test. Polycythemia vera is a rare condition that causes few effects in early stages but can cause serious complications as it progresses. It results in having too many red blood cells in your bloodstream. It is not hereditary, so you wouldn’t

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What to Eat When You Have Polycythemia Vera

Polycythemia vera can cause a variety of complications, and certain foods can increase your risk of conditions associated with polycythemia vera. Polycythemia vera is a chronic blood disorder in which the body makes too many red blood cells. This condition can cause a number of symptoms and complications. The disease is not caused by dietary factors, and it cannot be reversed or managed with

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Symptoms of Polycythemia Vera

Polycythemia vera is a blood disorder that causes slowly progressing effects and can lead to blood cancer. Learn about its symptoms and complications. Polycythemia vera is a blood disorder in which your body makes too many red blood cells. The condition may cause subtle symptoms, such as a generalized sense of fatigue, or it might not cause symptoms at all at an early stage.Over time, serious

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New and Upcoming Treatment Options for Primary Myelofibrosis

If first line treatments aren't effective in treating your myelofibrosis, your physician may look to clinical trials to choose a new treatment. The only curative therapy for primary myelofibrosis (PMF) is stem cell transplant, however, this therapy is recommended for high- and intermediate-risk patients only. Even in this group, age and other medical conditions can increase the risks

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Jakafi Targets Faulty Mechanism in Polycythemia Vera

Jakafi (ruxolitinib) was just approved to treat polycythemia vera. It is meant for people who can't take or don't benefit from hydroxyurea. We live in wondrous times where we not only better understand the mechanisms of disease but also how to target these mechanisms with newly discovered drugs. For instance, Jakafi (ruxolitinib) became the first FDA-approved drug to treat polycythemia

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An Overview of Myelofibrosis

Myelofibrosis, or agnogenic myeloid metaplasia, is a rare cancer-like illness of the bone marrow. It can lead to weakness, fatigue, and other symptoms. Myelofibrosis, also known as agnogenic myeloid metaplasia, is a rare and potentially serious disease of the bone marrow. It causes the marrow to develop fibrous tissue—scars, essentially—which, in turn, leads the marrow to produce abnormal blood

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Treatment Choices in Essential Thrombocythemia

Genetic mutations in essential thrombocythemia lead to extremely high platelet counts. Treatment is focused on preventing complications. Essential Thrombocythemia (ET) is one of a group of blood disorders called myeloproliferative neoplasms. Other types of myeloproliferative neoplasms include primary myelofibrosis and polycythemia vera.Genetic mutations in essential thrombocythemia

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Study: Gallstones May Come Before Pancreatic Cancer Diagnosis

A new study has found that people who were eventually diagnosed with pancreatic cancer often had gallstones years before the diagnosis. Key TakeawaysA new study found that people diagnosed with pancreatic cancer were six times more likely to have had gallstones in the year before getting diagnosed with cancer.People with a history of gallstones should be followed closely by their

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Monkeypox Outbreak Spreads to the U.S.

Learn what monkeypox is and why it's spreading in the United States. Key TakeawaysSmall outbreaks of a viral infection called monkeypox are occurring around the world.The United States has one confirmed case, with more expected.Monkeypox has a low fatality rate.An approved vaccine for monkeypox is estimated to be 85%

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